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Journal of Pharmaceutical Negative Results ; 13:3254-3265, 2022.
Article in English | EMBASE | ID: covidwho-2206768

ABSTRACT

In this study Evaluation of the Prevalence of Heart Problems in Patients with Covid-19 with High Blood Pressure and Diabetes in Patients Admitted to ICU was investigated. Due to the small number of some underlying diseases such as asthma, acute respiratory disease, liver, kidney and cancer, these diseases were merged together and entered as a variable. According to the results of univariate logistic regression, body mass index, diabetes and underlying diseases were related to contracting the Covid-19 disease, so that an increase of one unit of body mass index was 4% and diabetes and underlying diseases also had a 41% chance. It increased the incidence of Covid-19. All variables were entered into the multivariable regression model by enter method to calculate their simultaneous effect. Collinearity between quantitative variables was checked and rejected. After entering the variables into the multivariable logistic regression and observing the effect of each variable in the presence of other variables, almost the same results as the univariate regression were obtained. The results of the present study showed that the risk of hospitalization due to Covid-19 disease is significantly related to male gender and old age, because increasing age leads to defects in the body's immune system's response to pathogens and increases the rate of hospitalization. Also, the current research showed that blacks, obese people and smokers, as well as people with underlying diseases such as diabetes, cardiovascular diseases, kidney and high blood pressure, have the highest number of hospitalizations due to Covid-19. They are because the efficiency of the immune system response in these people is low, so it leads to severe type of disease and hospitalization. Many signs and symptoms in the elderly appear atypical or unusual. Copyright © 2022 Wolters Kluwer Medknow Publications. All rights reserved.

2.
Acta Paediatr ; 110(3): 914-921, 2021 Mar.
Article in English | MEDLINE | ID: covidwho-933963

ABSTRACT

AIM: Persistent symptoms in adults after COVID-19 are emerging and the term long COVID is increasingly appearing in the literature. However, paediatric data are scarce. METHODS: This paper contains a case report of five Swedish children and the long-term symptoms reported by their parents. It also includes a systematic literature review of the MEDLINE, EMBASE and Web of Science databases and the medRxiv/bioRxiv pre-print servers up to 2 November 2020. RESULTS: The five children with potential long COVID had a median age of 12 years (range 9-15) and four were girls. They had symptoms for 6-8 months after their clinical diagnoses of COVID-19. None were hospitalised at diagnosis, but one was later admitted for peri-myocarditis. All five children had fatigue, dyspnoea, heart palpitations or chest pain, and four had headaches, difficulties concentrating, muscle weakness, dizziness and sore throats. Some had improved after 6-8 months, but they all suffered from fatigue and none had fully returned to school. The systematic review identified 179 publications and 19 of these were deemed relevant and read in detail. None contained any information on long COVID in children. CONCLUSION: Children may experience similar long COVID symptoms to adults and females may be more affected.


Subject(s)
COVID-19/complications , Adolescent , Age Factors , COVID-19/diagnosis , COVID-19/epidemiology , Child , Female , Humans , Male , Symptom Assessment , Time Factors
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